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The drugs, acamprosate (marketing name: Campral) and naltrexone (ReVia) were found to help those struggling in different phases of recovery. Acamprosate helped manage emotional triggers in people that had already stopped drinking, naltrexone helped manage cravings in heavy drinkers who are looking to stop drinking or recently quit. Using two separate drugs to shed pounds can be very effective there are combinations while watching FDA now awaiting approval. When dealing with weight loss and the people that go through it you need to err to the side of caution and let the FDA do its job and demand some research be done in order that the public understands the side effects and hazards of the medications before we take them. Keep in mind that drug companies are in business to make money and that they would say almost anything to keep people on the medications. Researchers discovered that participants using this drug for any year, lost weight within four weeks and have kept the weight off through the 56 weeks in the study. Contrave is a combination of the drugs naltrexone and bupropion, which seems to reflect a new trend of weight-loss drugs that are made up of many active ingredient, that might make them far better and safer. Combo-pilling will be the newest fad or even better the newest ahead under scrutiny and for that reason it is just more publicly known although in the past, comb-pilling for losing weight has been around since the eighties. The biggest reason that employing a combination of pills is now popular could be the fact that by right now there are not any long term prescription weightloss pills that have been authorized by the FDA apart from orlistat. The truly disturbing part is the fact that doctors are prescribing these combinations of medications although some people might of the combinations are actually rejected or have yet to be authorized by the FDA. Seizures can be a side effect with Contrave and must not be taken in those with seizure disorders. The drug can also raise hypertension and pulse rate, and shouldn't be used in people with a history of cardiac arrest or stroke in the earlier six months. Blood pressure and pulse should also be measured before commencing the drug and throughout therapy with the drug. The FDA also warned that Contrave can raise blood pressure and heartrate and must 't be used in patients with uncontrolled high blood pressure level, in addition to by you aren't heart-related and cerebrovascular (circulation system dysfunction impacting mental performance) disease. Patients having a history of cardiac event or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded through the clinical trials. Those taking Contrave should have their heart-rate and pulse monitored regularly. In addition, since compound includes bupropion, Contrave comes using a boxed warning to alert physicians and patients towards the increased probability of suicidal thoughts and behaviors connected with antidepressant drugs. The warning also notes that serious neuropsychiatric events happen to be reported in patients taking bupropion for smoking cessation. "This could be the first drug I'm alert to that targets the appetite and reward centres inside the brain," he explained.